Which phase of ligament healing is characterized by maximal cellular activity and tissue repair?

The phase of ligament healing that is characterized by maximal cellular activity and tissue repair is the proliferative phase. During this phase, there is a significant increase in fibroblast activity, which is critical for synthesizing collagen and other extracellular matrix components necessary for healing. This phase typically follows the inflammatory phase, where initial healing processes begin, and precedes the remodeling phase, where the newly formed tissue matures and gains strength over time.

During the proliferative phase, angiogenesis also occurs, as new blood vessels form to supply nutrients and oxygen to the healing tissue. This increased cellular activity is essential for repairing the ligament, as it helps restore structural integrity and functionality. The biologic processes during this phase not only facilitate tissue repair but also lay the groundwork for long-term restoration of function.

In summary, the proliferative phase is crucial for cellular proliferation and repair, marking a period of dynamic activity vital for successful ligament healing.