What is a major goal in the maturation phase of wound healing?

In the maturation phase of wound healing, a primary objective is the increase of collagen synthesis and modification. During this phase, which can last from several weeks to years, the body continues to strengthen the wound site through the production and remodeling of collagen. Collagen serves as the main structural protein in the extracellular matrix and provides tensile strength to the tissue.

As the wound heals, collagen fibers undergo changes to become more organized and cross-linked, enhancing the structural integrity of the repaired tissue. This process significantly contributes to the overall healing and stability of the area, making it less prone to future injury.

While reduction of scar tissue is a related aspect of wound healing, the primary focus during maturation is on enhancing collagen modification, which is essential for proper tissue remodeling and function. Rapid epithelialization is more relevant in the inflammatory and proliferative phases, whereas the immediate inflammation response is critical to the initial healing process but is not a focus of the maturation phase.