What characterizes granulation tissue?

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Granulation tissue is characterized primarily by its composition, which includes new blood vessels and fibroblasts. This tissue typically forms during the healing process, particularly in the inflammatory and proliferative phases. The presence of new blood vessels, a process known as angiogenesis, is crucial as it supplies nutrients and oxygen to the healing area, promoting further tissue repair and regeneration. Fibroblasts are key cells in this process, responsible for synthesizing extracellular matrix components and collagen, which are essential for tissue strength and integrity.

This combination of vascularization and cellular activity is what distinguishes granulation tissue from other types of tissue, such as fully matured scar tissue, which is more developed and lacks the same degree of vascularity. The other options highlight features that do not accurately describe granulation tissue; it is not avascular, does not consist solely of collagen fibers, and does not have high concentrations of fat cells, which are characteristic of different tissue types. Understanding these features helps clarify the role of granulation tissue in the healing process and its importance in subsequent stages of repair.

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