What are growth factors and their significance in tissue repair?

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Growth factors are specialized polypeptides that play a crucial role in the process of tissue repair. They are signaling molecules that facilitate communication between cells, thereby triggering specific cellular responses needed for healing. When tissue is damaged, growth factors are released to stimulate various repair processes, such as cell proliferation, differentiation, and migration towards the injury site.

These factors are essential for orchestrating the complex interplay between different cell types involved in healing, including fibroblasts, endothelial cells, and immune cells. They not only enhance the regeneration of tissues but also help in the formation of new blood vessels, a process known as angiogenesis, which is critical for providing nutrients and oxygen to the healing area.

Understanding the role of growth factors is vital for developing effective rehabilitation strategies post-surgery, as they can influence outcomes significantly. Including therapies that modulate these factors can potentially improve recovery timelines and enhance the quality of repair in orthopedic rehabilitation.

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