How does regeneration differ from replacement in tissue repair?

Regeneration is characterized by the body's ability to restore tissue back to its original architecture and function after an injury. This process involves the proliferation of the same type of cells that were initially present in the tissue, allowing for a complete restoration. In contrast, replacement involves the formation of scar tissue, which does not mimic the original architecture or functionality of the tissue. This process usually occurs when the damage is too extensive for regeneration to occur. Instead of restoring the original function, replacement leads to healing with non-functional fibrous tissue, which can impact the overall functionality of the affected area.

Thus, the distinction lies in the outcomes of the healing processes: regeneration results in an accurate restoration of the tissue, while replacement provides a less effective solution with scarring.