How does granulation tissue appear as it matures?

Granulation tissue plays a crucial role in the healing process following injury or surgery. As it matures, it undergoes significant changes that contribute to the overall healing of the affected area. Initially, granulation tissue is characterized by a pink and soft appearance due to the presence of new blood vessels, inflammatory cells, and extracellular matrix components.

As healing progresses, this tissue becomes more substantial and firm, reflecting an increase in collagen deposition and the maturation of the extracellular matrix. This transformation is essential for providing the structural support necessary for tissue integrity and functionality.

This process is vital, as it lays the groundwork for later stages of healing, including remodeling into scar tissue, which can provide long-term stability to the repaired area. The maturation of granulation tissue is indicative of an effective healing response and is essential for reestablishing tissue integrity post-operatively.